Imagine working for a company that is working to go beyond treating the symptoms of genetic disease by trying to stop its progress at its underlying cause.
That’s what we do every day at Lexeo Therapeutics.
We’re not content to simply make better therapies – we want to change the arc of medicine. That passion drives us, and we look for it in every person we bring to our team.
Ready to be a part of it? See our openings below.
COMPANY BENEFITS:
Health Insurance & Wellness benefits
Health, dental and vision benefits
Flexible Spending Account (FSA)
Health Savings Account (HSA)
Disability insurance
Life insurance
Mental health benefits
Perks & Discounts
Commuter benefits
Tech stipend
Stocked kitchen
In office lunch stipend
Retirement & Stock option benefits
401(K) with company match
Performance bonus
Company equity
Vacation & Time off benefits
Unlimited PTO
Paid holidays
Paid parental leave
CMC
Research Associate, Process Development (Contract)
Onsite / Contract
New York, New York, US
The Contract Research Associate will be responsible for assisting in the development and optimization of the production and purification of AAV therapies in Lexeo's NYC lab. The successful candidate will master the downstream purification process and become a driver of process innovation. The Contract Research Associate will have the opportunity to learn at a fast-paced startup company with multiple ongoing clinical trials for novel cardiac and neurodegenerative gene therapies. The Research Associate’s work will directly impact ongoing and future clinical trials.
Essential Duties and Responsibilities
Perform downstream purification process development and optimization for LEXEO’s industry leading gene therapy manufacturing process
Participate/collaborate closely with the analytical development team to evaluate gene therapy product characterization, critical quality attributes, and process performance parameters
Prepare manufacturing process data summaries, process descriptions, process reports, and technology transfer reports
Present process improvement work to the broader company and contribute to external presentations
Engage with external partners including CMO/manufacturing teams and analytical partners
Purify vector for internal pre-clinical studies
Assist with process planning and resourcing to ensure alignment with company timelines
Perform other duties as required
Qualifications
BS/MS or equivalent in biology, biochemistry, or other relevant life science
Hands on laboratory experience in biologics with an understanding of lab safety
An understanding of virus/viral vector properties and experience with the development of downstream or upstream processes for viral vectors/gene therapy products are highly desirable
Hands-on experience with AKTA chromatography and filtration systems is a plus
Understanding of the fundamentals of chromatography and/or membrane separations preferred
Prior experience with characterizing and troubleshooting bioprocessing methods
Strong verbal and written communication skills
Enthusiasm and curiosity for the science behind creating world class AAV therapies!
$0 - $0 a year
LEXEO Therapeutics is a New York City-based, clinical-stage gene therapy company focused on addressing some of the most devastating genetically defined cardiovascular and central nervous system diseases affecting both larger-rare and prevalent patient populations. LEXEO’s foundational science stems from partnerships and exclusive licenses with leading academic laboratories at Weill Cornell Medicine and the University of California, San Diego. LEXEO is advancing a deep and diverse pipeline of AAV-based gene therapy candidates in rare cardiovascular diseases and APOE4-associated Alzheimer’s disease and is led by pioneers and experts with decades of collective experience in genetic medicines, rare disease drug development, manufacturing, and commercialization.
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
We're always on the lookout for talented people who are excited about what we’re building at Lexeo Therapeutics. If you don’t see a role that fits your background, but feel like you could add value to our team, we’d love to hear from you!
This is an open application for any future opportunities across the organization, including internships.
What We're Looking For:
- Passion for our mission and values
- Strong communication and collaboration skills
- A proactive mindset
- Curiosity and willingness to learn
What You Can Expect:
- We’ll review your application and keep it on file to be considered for current or future openings
- If there’s a potential match, we’ll reach out to start a conversation
- It may take a while for any relevant roles to be available. Please continue to keep an eye on our careers site as well for any opportunities that may align with your experience
We appreciate your interest!
$64,350 - $400,000 a year
About Lexeo
Lexeo Therapeutics is a New York City-based, clinical stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimer’s disease are treated. Using a stepwise development approach, Lexeo is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of clinical and preclinical programs. Lexeo successfully completed a $112M IPO in November 2023 and in early March 2024 announced a PIPE raising an additional $95M, extending the Company’s runway into 2027.
Our work culture for most roles is a hybrid model with days in the New York City office and days working from home. We welcome applications from candidates located across the Northeast and Mid-Atlantic. Remote work can be considered for exceptional candidates.
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
