Careers
- Imagine working for a company that is working to go beyond treating the symptoms of genetic disease by trying to stop its progress at its underlying cause.
- That’s what we do every day at Lexeo Therapeutics.
- We’re not content to simply make better therapies – we want to change the arc of medicine. That passion drives us, and we look for it in every person we bring to our team.
- Ready to be a part of it? See our openings below.
COMPANY BENEFITS:
Health Insurance & Wellness benefits
- Health, dental and vision benefits
- Flexible Spending Account (FSA)
- Health Savings Account (HSA)
- Disability insurance
- Life insurance
- Mental health benefits
Perks & Discounts
- Commuter benefits
- Tech stipend
- Stocked kitchen
- In office lunch stipend
Retirement & Stock option benefits
- 401(K) with company match
- Performance bonus
- Company equity
Vacation & Time off benefits
- Unlimited PTO
- Paid holidays
- Paid parental leave
Clinical Development
Associate Director, Patient Advocacy
- Hybrid / Full time
- New York, New York, US
As the Associate Director of Patient Advocacy, you will play a pivotal role in ensuring that the patient voice is heard and integrated into all aspects of Lexeo’s activities. You will be responsible for developing and implementing strategies to engage with patient advocacy groups and patient communities to understand patient perspectives and address unmet needs. By collaborating closely with cross-functional teams, you will help drive initiatives that prioritize patient-centricity and improve patient outcomes.
Primary Responsibilities
- Develop and execute a patient advocacy strategy aligned with the company's overall objectives and values.
- Build and maintain relationships with Global patient advocacy groups to foster collaboration and partnership.
- Lead patient advisory boards and focus groups to better understand patient diagnostic journey, patient preferences, and educational gaps.
- Communicate insights from patient and advocacy group interactions with cross-functional team members to inform program strategies and clinical development plans.
- Provide guidance and support to internal teams on best practices for engaging with patients.
- Serve as a liaison between the company and patient communities, ensuring that their perspectives are considered in decision-making processes.
- Lead the development and implementation of patient-centric initiatives, programs, and resources, such as educational materials and advocacy campaigns.
- Represent the company at patient-focused conferences, events, and meetings.
- Collaborate with cross-functional teams, including Medical Affairs, Marketing, Market Access, Regulatory Affairs, and Clinical Development, to ensure alignment and integration of patient advocacy efforts across the organization.
- Track and measure the impact of patient advocacy initiatives and provide regular updates and reports to senior management.
Required Skills & Qualifications
- Minimum 3 years of relevant professional experience
- Undergraduate degree required
- Master's Degree in related field (genetics, public health, etc.) preferred
- Strong track record of developing and supporting successful patient advocacy strategies and communications with excellent written and oral communication skills
- Experience in gene therapy, cardiology, and/or rare diseases preferred
$163,000 - $195,000 a year
Base salary dependent on qualifications and overall experience.
About Lexeo
Lexeo Therapeutics is a New York City-based, clinical stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimer’s disease are treated. Using a stepwise development approach, Lexeo is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of clinical and preclinical programs. Lexeo successfully completed a $112M IPO in November 2023 and in early March announced a PIPE raising an additional $95M, extending the Company’s runway into 2027.
Our work culture for most roles is a hybrid model with days in the New York City office and days working from home. We welcome applications from candidates located across the Northeast and Mid-Atlantic. Remote work can be considered for exceptional candidates.
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
Apply now
G&A
Executive Assistant
- Onsite / Full time
- New York, New York, US
We are seeking a highly organized, detail-oriented Executive Assistant to join the team and uplift the work of the executive team. This includes diligent calendar management, travel coordination, correspondence, expense management, and coordinating and supporting ad hoc administrative projects. The incumbent must be a self-starter and enthusiastic about supporting the executive team. The Executive Assistant will ensure strong team coordination across departments and Executives. We are looking for a candidate who communicates with ease via email and on the phone, can anticipate needs, is highly organized, and is passionate about the company’s mission.
You will be a strong fit if you enjoy being part of a team with big ambitious ideas and you gain energy from bringing a smooth systematic process to manage the chaos. You are comfortable working in a fast-paced team environment with some level of ambiguity in which decisions are made quickly and support the evolving needs of the business. You are a clear and kind communicator and proactively bring things up to your colleagues that need to be discussed. You are open to new ideas and feel great when you hit or exceed your goals.
This role requires an in-office presence 5 days a week; dependent on business needs.
Primary Responsibilities
- Extensive coordination and scheduling of internal and external meetings, conference calls, and video conference meetings, utilizing Outlook and Video Conferencing on behalf of supported Executives
- Manageonsite and offsite meetings, including arranging for any catering and document distribution, IT needs
- Prioritize Outlook calendar items and resolve calendar conflicts, informing Executive of meeting changes and keeping them on schedule throughout the day
- Coordinate set up and clean up of conference rooms
- Management of international and domestic travel, meeting coordination, expense reports and logistics for the executive(s), and triaging changes as they arise
- Act as the point of contact among executives, employees, clients, and other external partners
- Manage information flow in a timely and accurate manner
- Support office management needs as they arise
- Assist other Admins. in firm-wide tasks when requested
- Organize and maintain the filing of relevant documents
Required Skills & Qualifications
- A minimum of 8 years of experience, in progressive administrative functions
- Previous track record of success in supporting C-suite level executives required
- Highly professional phone and written communication skills
- Excellent problem-solving capabilities, with timely resolution, demonstrating an ability to work independently with limited guidance and exercise independent judgment, including knowing when to elevate concerns or issues.
- Technology savvy and willing to learn new systems in a short time
- Highly responsive and able to work on evenings and weekends when needed to support business needs
- Self-starter with a willingness to do what it takes to fulfill all relevant work requests and ensure a smooth outcome on matters large and small
- Eager, can-do attitude, willing and wanting to learn and take on projects as needed in a dynamic environment
- Prior experience in a start-up environment is strongly preferred
- Excellent MS Office knowledge
- Outstanding organizational and time management skills
- Excellent verbal and written communication skills
- Discretion and confidentiality
$90,000 - $115,000 a year
About Lexeo
Lexeo Therapeutics is a New York City-based, clinical stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimer’s disease are treated. Using a stepwise development approach, Lexeo is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of clinical and preclinical programs. Lexeo successfully completed a $112M IPO in November 2023 and in early March announced a PIPE raising an additional $95M, extending the Company’s runway into 2027.
Our work culture for most roles is a hybrid model with days in the New York City office and days working from home. We welcome applications from candidates located across the Northeast and Mid-Atlantic. Remote work can be considered for exceptional candidates.
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
Apply now
Manager, Commercial Strategy
- Hybrid / Full time
- New York, New York, US
The Manager, Commercial Strategy will play a pivotal role in shaping the commercial direction of Lexeo’s leading cardiac programs. With multiple interim data readouts expected in 2024, it is crucial to define and refine commercial assumptions as these programs advance, and to support the expansion of Lexeo’s growing commercial organization and capabilities. This role focuses on characterizing the current and evolving landscape in gene therapy and rare cardiovascular disease, particularly Friedreich ataxia (FA) cardiomyopathy and arrhythmogenic cardiomyopathy (ACM). Additionally, this role will encompass commercial operations responsibilities, ensuring seamless execution of commercial plans and strategies.
*Remote candidates within the United States will be considered for this role.
Primary Responsibilities
- Conduct market research, including primary and secondary research, to outline market dynamics in FA and ACM, such as unmet needs, key stakeholders, existing treatment paradigms, and competition, focusing on the U.S. and key international markets.
- Leverage research and insights to define how the company’s gene therapy candidates may meet unmet needs and impact future treatment paradigms.
- Collaborate closely with clinical colleagues to understand target product profiles and identify patient populations eligible for treatment.
- Identify and map key stakeholders involved in the treatment of FA and ACM, as well as those involved in the potential administration of cardiac gene therapy.
- Compile information on current treatment costs, payer perspectives, patient coverage types, treatment expenditure, and other medical costs.
- Analyze commercially available gene therapies in key markets, identifying successful constructs that maximize patient access or enable value-based reimbursement.
- Outline recommended investments and timelines for commercial scale-up over the next three years, including necessary commercial capabilities and colleagues.
- Develop and implement operational plans to ensure the efficient execution of commercial strategies.
- Monitor and evaluate the performance of commercial initiatives, providing insights and recommendations for continuous improvement.
- Advance Lexeo objectives commercially, including support for corporate communications, media awareness, and internal employee initiatives that increase knowledge and understanding of lead programs and strategies
- Work closely with colleagues in Clinical Development, Medical Affairs, Program Management, and other relevant departments to ensure cohesive strategy execution.
- Report to the Senior Director of Commercial Development, regularly updating on project progress and strategic recommendations.
- Present findings and strategic recommendations to company leadership, facilitating informed decision-making.
Required Skills & Qualifications
- MBA with 7-10 years of professional experience in consulting, finance, marketing, sales, or biopharmaceuticals, with a focus on commercial strategy and operations.
- Experience in the healthcare and biopharmaceutical industry, with a deep understanding of global biopharmaceutical market trends.
- Proven ability to synthesize data from multiple sources and distill insights into clear, actionable business strategies.
- Strong project management skills with meticulous attention to detail and the ability to manage multiple priorities in a fast-paced environment.
- Excellent interpersonal communication skills and a track record of successful cross-functional collaboration.
- Ability to operate independently, driving projects to completion with minimal oversight.
$114,000 - $165,000 a year
About Lexeo
Lexeo Therapeutics is a New York City-based, clinical stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimer’s disease are treated. Using a stepwise development approach, Lexeo is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of clinical and preclinical programs. Lexeo successfully completed a $112M IPO in November 2023 and in early March announced a PIPE raising an additional $95M, extending the Company’s runway into 2027.
Our work culture for most roles is a hybrid model with days in the New York City office and days working from home. We welcome applications from candidates located across the Northeast and Mid-Atlantic. Remote work can be considered for exceptional candidates.
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
Apply now
Regulatory
Director/Senior Director, Medical Writing
- Hybrid / Full time
- New York, New York, US
The Director/Senior Director, Medical Writing will lead the Medical Writing function at Lexeo, working cross-functionally to generate and oversee the development of clinical and regulatory documents across all company programs. This role will be responsible for the planning, development, and oversight of study and program level documents with a focus on accuracy, quality, and compliance. Additionally, the role will manage medical writing resources, including vendors and partners, and contribute to process improvement initiatives.
Hybrid is preferred for this role, but we are open to remote candidates within the US willing to work on Eastern time zone hours.
Primary Responsibilities
- Serve as the Medical Writing Lead for Lexeo’s clinical development programs.
- Oversee medical writing resource planning, budgeting, and project planning and execution.
- Draft and direct the writing of company regulatory and clinical documents, including but not limited to Investigator Brochures, IND and CTA Amendments, annual reports, Health Authority briefing documents, clinical trial protocols and amendments, clinical study reports, and summaries.
- Manage the document development process for deliverables including planning aspects (timeline development, kick-off meetings, communicating scope and accountabilities), project execution (tracking/monitoring progress according to established timelines, conducting team meetings), and project finalization (ensuring final agreed content, approval, quality, and compliance).
- Oversee regulatory operations and publishing.
- Ensure the quality of deliverables by conducting editorial review of documents (grammar, punctuation, consistency) and completing or managing the quality checking of documents.
- Oversee vendor identification, engagement, and management to enable completion of objectives and corporate priorities.
- Identify and implement organization efficiencies for document development and quality, document management, and submission management.
- Build and maintain collaborative relationships with medical writing and regulatory partners (contractors, FTE, CROs, and the writing community).
- Facilitate the development and maintenance of standard processes and style guides.
- Serve as the StartingPoint Administrator, managing template upgrades, internal user support, and cross-departmental training.
- Provide oversight for the development of more junior colleagues.
- Contribute to department initiatives and other duties in support of clinical development as needed.
Required Skills & Qualifications
- A bachelor's degree is required; a graduate degree (Master's or Ph.D.) is strongly preferred. At least one of these degrees must be in a scientific discipline.
- Minimum of 8 years experience with at least 4 to 6 years working as a medical writer within a pharmaceutical/biotech company or CRO.
- Direct experience leading the development of protocols and amendments, clinical study reports (CSRs), IBs, and the ability to generate most types of clinical and regulatory medical writing deliverables.
- Working knowledge of the content and format of the electronic Common Technical Document (eCTD) and document publishing specifications.
- Thorough knowledge of the drug development process and applicable regulatory requirements and guidelines (e.g., ICH E3, E6, E9).
- Advanced writing and speaking competency, positive and proactive written and verbal communication skills.
- Experience across all phases of clinical development and with most types of regulatory and clinical documents, including highly complex documents.
- Demonstrated ability to translate complex technical information from mixed sources into written information suitable for an audience of clinicians and health authorities.
- Demonstrated high attention to detail in overall document consistency and strategic presentation of information.
- Ability to manage multiple projects simultaneously in a fast-paced environment.
- Proficiency in Microsoft Office Suite (including MS Project) and Adobe Acrobat as well as authoring toolbars and template suites (Starting Point experience preferred) and reference software.
- Ability to adapt and work effectively in changing situations and different program teams.
$175,000 - $275,000 a year
About Lexeo
Lexeo Therapeutics is a New York City-based, clinical stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimer’s disease are treated. Using a stepwise development approach, Lexeo is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of clinical and preclinical programs. Lexeo successfully completed a $112M IPO in November 2023 and in early March announced a PIPE raising an additional $95M, extending the Company’s runway into 2027.
Our work culture for most roles is a hybrid model with days in the New York City office and days working from home. We welcome applications from candidates located across the Northeast and Mid-Atlantic. Remote work can be considered for exceptional candidates.
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
Apply now