Careers

  • Imagine working for a company that is working to go beyond treating the symptoms of genetic disease by trying to stop its progress at its underlying cause.
  • That’s what we do every day at Lexeo Therapeutics.
  • We’re not content to simply make better therapies – we want to change the arc of medicine. That passion drives us, and we look for it in every person we bring to our team.
  • Ready to be a part of it? See our openings below.

COMPANY BENEFITS:

Health Insurance & Wellness benefits

  • Health, dental and vision benefits
  • Flexible Spending Account (FSA)
  • Health Savings Account (HSA)
  • Disability insurance
  • Life insurance
  • Mental health benefits

Perks & Discounts

  • Commuter benefits
  • Tech stipend
  • Stocked kitchen
  • In office lunch stipend

Retirement & Stock option benefits

  • 401(K) with company match
  • Performance bonus
  • Company equity

Vacation & Time off benefits

  • Unlimited PTO
  • Paid holidays
  • Paid parental leave

CMC

Contract Quality Control Research Associate

  • Onsite / Contract
  • New York, New York, US
The Contract QC Research Associate will support the CMC Quality Control (QC) function by coordinating all aspects of sample management(including, but not limited to: storage, documentation, submission, and shipment) to internal and external testing laboratories. This role ensures timely and accurate execution of sample testing activities to support product release, stability programs, and other analytical requirements. Additionally, this role will help organize, trend, interpret, and summarize the data resulting from testing. 

Primary Responsibilities

  • Serve as primary contact for QC Lab Support processes such as laboratory inventory management,  sample submission, sample receiving.. 
  • Prepare and manage sample submission paperwork for external contract testing labs (CTLs), including quotes, purchase orders, shipping documents. 
  • Coordinate shipment of samples, reference standards, and reagents to and from manufacturing sites, external vendors, and CTLs in compliance with storage and shipping requirements. 
  • Track sample testing from submission through completion; receive and organize Certificates of Analysis (CoAs), Certificates of Testing (CoTs), and other QC data packages. 
  • Coordinate with vendors and support vendor testing activities by ensuring report documentation packages are complete and organized. 
  •  Configure and maintain the LIMS system to support controlled temperature unit (CTU) inventory and sample tracking requirements. 
  • Enter and manage sample data in LIMS; ensure accurate labeling, categorization, and documentation. 
  • Generate sample labels with unique identifiers (e.g., barcodes or QR codes) and ensure physical organization of samples in alignment with electronic records. 
  • Collaborate with cross-functional CMC teams to align on sample submission and testing needs. 

Required Skills & Qualifications

  • Bachelor’s degree in a scientific discipline (e.g., Chemistry, Biology, Biotechnology) 
  • Hands on experience in pharmaceutical/biotech QC, sample management, or logistics with an understanding of lab safety; knowledge of IATA RCA and DOT guidelines a plus 
  • Experience with LIMS and laboratory sample tracking systems; familiarity with Benchling or Quartzya plus. 
  • Strong organizational skills with attention to detail and accuracy. 
  • Ability to manage multiple priorities and meet deadlines in a fast-paced environment. 
  • Excellent communication and coordination skills. 
  • Knowledge of GMP/GxP requirements for sample handling, testing, and documentation preferred. 
About Lexeo

LEXEO Therapeutics is a New York City-based, clinical-stage gene therapy company focused on addressing some of the most devastating genetically defined cardiovascular and central nervous system diseases affecting both larger-rare and prevalent patient populations. LEXEO’s foundational science stems from partnerships and exclusive licenses with leading academic laboratories at Weill Cornell Medicine and the University of California, San Diego. LEXEO is advancing a deep and diverse pipeline of AAV-based gene therapy candidates in rare cardiovascular diseases and APOE4-associated Alzheimer’s disease and is led by pioneers and experts with decades of collective experience in genetic medicines, rare disease drug development, manufacturing, and commercialization

Our work culture is a hybrid model with 2 days/week in the New York City office and days working from home.  
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
Apply now

G&A

Director/Sr. Director, Capital Markets Finance

  • Hybrid / Full time
  • New York, New York, US
We are seeking a dynamic Capital Markets team member, preferably with a background in investment banking or equity research, to build, and execute, a best-in-class capital markets strategy. This role will be the primary liaison to analysts and investors, while also serving as a trusted advisor to senior leadership on how Wall Street views our strategy, pipeline, and financial performance. 

The successful candidate thrives at the intersection of finance, science, and storytelling, translating complex clinical and operational data into compelling investor-ready narratives that resonate with institutional investors and analysts. 

Primary Responsibilities

  • In partnership with Lexeo leadership, build a world-class capital markets program, overseeing all messaging, external communications, and investor engagement strategy 
  • Partner with the CEO, CFO, and senior leadership on quarterly earnings, roadshows, analyst days, and capital markets initiatives 
  • Coordinate preparation of investor-facing materials: earning scripts, Q&A prep, press releases and corporate presentations 
  • Serve as a spokesperson for the company with institutional investors and analysts
  • Monitor sell-side coverage, investor sentiment, peer activity, and sector dynamics to anticipate market reactions 
  • Build and maintain sophisticated financial models, comps, and valuation scenarios to inform both investor messaging and internal decision-making 
  • Provide leadership with insights into market opportunities, risks, and investor priorities. 
  • Prepare and/or deliver investor-informed readouts of clinical, operational, and R&D data to executives and the Board. 
  • Advise internal teams on framing pipeline milestones, trial timelines, and value drivers for Wall Street. 
  • Partner with leadership to refine pipeline and corporate strategy through the lens of investor expectations. 
  • Coordinate quarterly earnings process end-to-end, including script, deck, Q&A prep, and messaging 
  • Manage investor conferences, non-deal roadshows, analyst days, and targeted outreach programs 
  • Ensure all external communications comply with SEC and regulatory requirements 
  • Conduct benchmarking of peers’ pipelines, valuation frameworks, and investor narratives. 
  • Translate insights into actionable recommendations for internal strategy and external messaging 

Required Skills & Qualifications

  • Bachelor’s degree in finance, economics, business, or life sciences required; MBA or CFA strongly preferred. Medical or scientific background a plus.  
  • 7-10 years in capital markets, investor relations, equity research, investment banking, or corporate strategy 
  • Biotech/pharma experience preferred; must demonstrate ability to interpret and communicate complex clinical data 
  • Proven track record of direct engagement with institutional investors, analysts and capital markets stakeholders  
  • Strong financial modeling, valuation, and market analysis expertise 
  • Exceptional communication and executive presence, with ability to influence both internal leaders and external stakeholders 

$200,000 - $250,000 a year

Compensation is dependent on qualifications and experience.
About Lexeo

LEXEO Therapeutics is a New York City-based, clinical-stage gene therapy company focused on addressing some of the most devastating genetically defined cardiovascular and central nervous system diseases affecting both larger-rare and prevalent patient populations. LEXEO’s foundational science stems from partnerships and exclusive licenses with leading academic laboratories at Weill Cornell Medicine and the University of California, San Diego. LEXEO is advancing a deep and diverse pipeline of AAV-based gene therapy candidates in rare cardiovascular diseases and APOE4-associated Alzheimer’s disease and is led by pioneers and experts with decades of collective experience in genetic medicines, rare disease drug development, manufacturing, and commercialization

Our work culture is a hybrid model with 2 days/week in the New York City office and days working from home.  
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
Apply now